International Name (Active Ingredient): Comb. drug
Clinical-Pharmacological Group: Biologically active supplements → Immunology →
Immunomodulators → Immunostimulatory agents
Manufacturer: Narture Pharma
Country of Manufacture: Spain
Dosage Form: Capsule #15
Dispensing Mode: Group III (Over-the-counter)
Pharmacological Action:
Difens is a herbal immunostimulant with antioxidant and general tonic properties. It
reduces the risk of disease development, the duration of illnesses, and recurrence
frequency. It exhibits antiviral activity, with its effects based on the synergistic action of
its components.
Echinacea has immunostimulatory and anti-inflammatory properties. It enhances
the body's resistance to viral, bacterial, and fungal infections by boosting natural
defenses. Echinacea supports the production of immune-active substances like
interferon and strengthens both cellular and humoral immunity.
• Vitamin C is a potent antioxidant that enhances the body's resistance to harmful
environmental factors, stress, and infections. It also decreases blood vessel
permeability.
•Propolis exhibits antimicrobial properties, stimulating both specific and
nonspecific immunity factors. It enhances phagocytic function, increases
immunoglobulin levels, and destroys bacteria, viruses, and fungi. Propolis
contains flavonoids with anti-inflammatory effects, especially useful in
inflammatory conditions affecting the bones, joints, skin, and mucous
membranes.
•Indications for Use:
•Strengthening the body's immune status
•Prevention of flu and other acute respiratory infections
• Chronic recurrent inflammatory diseases of various localizations and etiologies,
including:
• Pathologies of the skin and mucous membranes
• Diseases of the urinary system
• Upper respiratory tract infections
• Chronic inflammatory diseases of the throat and ears
• Acute and chronic sinusitis
• Frequent illnesses
•Body exhaustion
Dosage and Administration:
• Children aged 3 years and above: 1 capsule in the morning, regardless of food
intake.
• Adults and children aged 12 years and above: 2 capsules in the morning,
regardless of food intake. Capsules should be swallowed whole with a small
amount of liquid.
• Treatment duration: 6–8 weeks. A prophylactic course is recommended twice a
year.
Side Effects:
Generally well tolerated. Rarely, hypersensitivity reactions may occur.
Contraindications:
• Individual hypersensitivity to any components
• Progressive systemic diseases such as tuberculosis, leukemia, and autoimmune
disorders
Pregnancy and Lactation:
The safety of the drug during pregnancy and lactation has not been studied.
Warnings and Storage:
•This dietary supplement should not replace a varied and balanced diet or a
healthy lifestyle.
•Do not exceed the recommended daily dose.
• Store in a dry, dark place out of reach of children.
