Clinical-pharmacological group: Central nervous system → Anxiolytics and hypnotics
Manufacturer: Narture Pharma
Country of manufacture: Spain
Dosage form: Capsule #30
Dispensing regimen: Group III (over-the-counter)
Composition:
- Dry extract of Valerian root (Valeriana officinalis) – 50 mg
- Dry extract of Lemon balm (Melissa officinalis) – 38 mg
- Extract of St. John’s Wort flowers (Hypericum perforatum) – 25 mg
- Extract of Lime flowers (Tilia platyphyllos cordata) – 25 mg
- Extract of Passionflower flowers (Passiflora incarnata) – 25 mg
- Extract of Peppermint leaves (Mentha piperita) – 25 mg
- Extract of Hops cones (Humulus lupulus) – 25 mg
Excipients: Microcrystalline cellulose, magnesium stearate, bovine gelatin capsule
Indications: Restlessness, anxiety, mild forms of neurasthenia, post-stress conditions, fear accompanied by tension, tachycardia, and wheezing; increased excitability, irritability, emotional tension or depression; decreased concentration, sleep disorders, headaches, and migraines caused by nervous tension with increased blood pressure; climacteric syndrome; persistent tension state – angioneurosis and vegetative neurosis.
Pharmacological Properties: Valerian root contains essential oils such as borneol and iso-valerenic acid esters, free valerianic acid, alkaloids, bitter substances, and others. Valerian reduces the excitability of the central nervous system, facilitates and enhances the natural sleep process. It has a spasmolytic effect. Linden flowers contain flavonoids, carotene, essential oils, bitter substances, and macro- and microelements. Linden exhibits calming, sedative, antihypertensive, and analgesic properties. Melissa (Lemon balm) is rich in essential oils (citral, geraniol), flavonoids (luteolin, rosmarinic acid), phenolic compounds, vitamins (A, C, B1, B2), and organic acids. Melissa alleviates anxiety, panic, fear, and attacks, and shows antioxidant properties. St. John’s Wort leaves contain flavonoids (hypericin, quercetin, isoqercetin), azulene, bitter substances, essential oils, and vitamins, which provide antidepressant, anti-anxiety, and calming effects. Passionflower flowers contain the flavonoid passiflorin, which acts on GABA receptors and produces a sedative effect. The alkaloids harman and norharman inhibit MAO release and promote serotonin, norepinephrine, and dopamine absorption, which improves mood and exerts antidepressant effects. Passionflower also has anticonvulsant properties. Peppermint contains a large amount of essential oil menthol, carotene, flavonoids, triterpenoid compounds, and various acids, which contribute to its anti-stress, calming, and spasmolytic actions. It causes reflexive dilation of coronary blood vessels. Hops contain the alkaloid lupulone and humulene, essential oils like myrcenodiol, farnesene, flavonoid glycosides, resinous substances, vitamins, and others. Hops exhibit a calming effect on the central nervous system, sedative effects, and analgesic properties.
Dosage and Administration: Tranquiplant is taken as 1-2 capsules once a day, unchewed, with a small amount of liquid.
Contraindications: Hypersensitivity to any of the active or excipient ingredients in the preparation.
Warnings and Storage Conditions: This dietary supplement should not be used as a substitute for a varied and balanced diet and healthy lifestyle. Do not exceed the recommended daily dose. Store in a dry, dark place, out of reach of children.
